TTP deficiency syndrome development abolished in absence of IL23. (A) Growth curves of IL23p19^+/+ TTP^+/+, IL23p19^+/+ TTP^−/−, and IL23p19^−/− TTP^−/− male mice (left), and growth curves of IL17A^+/+ TTP^+/+, IL17A^+/+ TTP^−/−, and IL17A^−/− TTP^−/− male mice (right). Similar data were obtained with female mice (not depicted). For these experiments, p19^+/− TTP^+/− mice or IL17A^+/− TTP^+/− mice were used as breeders and we compared IL23p19^+/+ TTP^−/− with IL23p19^−/− TTP^−/− littermates or IL17A^+/+ TTP^−/− with IL17A^−/− TTP^−/− littermates. Mean ± SEM from ≥9 mice is shown. (B and C) Representative H&E-stained sections of the skin or the joint of TTP^+/+, TTP^−/−, IL23p19^−/− TTP^−/−, and IL17A^−/− TTP^−/− mice. Bars, 100 µm.