Figure 4.

Gene expression profiles of m/chDC versus microglia, monocytes, and spleen DCs. Bone marrow monocytes, spleen (Spl) CD8+ and CD8 DC subsets from untreated B6 mice and brain m/chDCs, and microglia from B6 mice treated with Flt3L were purified, and mRNA was extracted for Affymetrix gene array analysis. (A–E) Graphs show normalized data comparison among the indicated cells for expression of receptors for growth factors (A), cell surface markers (B), pattern recognition molecules (C), antigen presentation and co-stimulatory molecules (D), and transcription factors (E). Error bars indicate mean ± SEM (n = 3).

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