Figure 5.
Figure 5. α4−/− mice develop atypical EAE. EAE was induced in α4−/− mice or wild-type control animals by immunization with MOG35-55 in CFA and disease severity was monitored according to the classical EAE score (mean clinical score + SEM, n = 5). Note that α4−/− mice developed an ataxic EAE syndrome whose severity is only partially reflected in the classical EAE score.

α4−/− mice develop atypical EAE. EAE was induced in α4−/− mice or wild-type control animals by immunization with MOG35-55 in CFA and disease severity was monitored according to the classical EAE score (mean clinical score + SEM, n = 5). Note that α4−/− mice developed an ataxic EAE syndrome whose severity is only partially reflected in the classical EAE score.

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