Peritoneal neutrophil influx in thioglycollate-induced peritonitis is elevated in Adamts13^−/− mice. Total neutrophil count in lavage was counted after 4 h of thioglycollate administration. (A) A significant increase in neutrophil extravasation was observed in Adamts13^−/− compared with Adamts13^+/+ mice. (B) No significant increase in neutrophil influx in the peritoneum was observed in Adamts13^−/−/Vwf^−/− compared with Adamts13^+/+/Vwf^−/− mice, indicating that this effect is dependent on VWF. Data represent the mean ± SEM.