Interchange of the SF conductive modes at 5 and 150 mM external K ⁺ conditions. Diagrams show the sequence of ion permeation events over the course of individual MD simulations. The passage of potassium ions was considered as complete and marked on the diagram when the distance between the center of corresponding K⁺ atom in the selectivity filter and the center of mass of four G316 oxygen atoms exceeded 4 Å.