Figure S2. Hydrophobic nature of the... | Rockefeller University Press

Figure S2.

Hydrophobic nature of the gate. Left: Scatter plots showing the correlation between free energy changes for mutation X in kcalmol−1 (ΔΔG0) versus standard chemical transfer energy (ΔGtrans) for the corresponding residues when 9′L/13′V is mutated to X in different subunits. Right: Identical correlation plots for all other hydrophobic residues between 2′ and 18′ in different subunits. Linear regression (unbroken straight lines) and confidence limits (dotted lines) are shown separately for each plot.

Hydrophobic nature of the gate. Left: Scatter plots showing the correlation between free energy changes for mutation X in kcalmol⁻¹ (ΔΔG₀) versus standard chemical transfer energy (ΔG^trans) for the corresponding residues when 9′L/13′V is mutated to X in different subunits. Right: Identical correlation plots for all other hydrophobic residues between 2′ and 18′ in different subunits. Linear regression (unbroken straight lines) and confidence limits (dotted lines) are shown separately for each plot.