Comparison of the contractile parameters in response to the pressure step protocol in IALVs from Ip3r1ismKO mice compared ICTismKO. (A–F) Analysis of the summarized contractile parameters (A) frequency, (B) amplitude, (C) tone, (D) MaxD, (E) EF, and (F) FPF at each experimental pressure. n = 12 Ip3r1ismKO (same data as in Fig. 3) and n = 9 for ICTismKO except for tone and MaxD where n = 7 due to debris interfering with tracking after Ca²⁺ free equilibration with mean and SEMs shown.