Figure 8. The SF of hTPC2 displays... | Rockefeller University Press

Figure 8.

The SF of hTPC2 displays similarities to both Ca2+-selective and Na+-selective channels. (A) Close-up view of adjacent filter I and filter II structures forming the SF. (B) Sequence comparison between filter I and filter II and Ca2+-selective or Na+-selective TRP channel SF sequences, respectively. Residue color code: Hydrophobic, red; polar and glycine, tan; acidic, blue.

The SF of hTPC2 displays similarities to both Ca²⁺-selective and Na⁺-selective channels. (A) Close-up view of adjacent filter I and filter II structures forming the SF. (B) Sequence comparison between filter I and filter II and Ca²⁺-selective or Na⁺-selective TRP channel SF sequences, respectively. Residue color code: Hydrophobic, red; polar and glycine, tan; acidic, blue.