Figure 13.
Differential effects of nocodazole on newly translated versuss existing NaV1.5. (A and B) Disrupting microtubules by nocodazole (10 µM, 12 h) prevented newly translated GFP-NaV1.5 from reaching the lateral surface and intercalated discs (A), but did not alter the distribution pattern of native NaV1.5 in ventricular myocytes (B). Scale bars are 10 μm.

Differential effects of nocodazole on newly translated versuss existing NaV1.5. (A and B) Disrupting microtubules by nocodazole (10 µM, 12 h) prevented newly translated GFP-NaV1.5 from reaching the lateral surface and intercalated discs (A), but did not alter the distribution pattern of native NaV1.5 in ventricular myocytes (B). Scale bars are 10 μm.

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