Figure 4.
Comparison of tail interactions with the SH3 and converter domains in atomic models of tarantula thick filaments and 10S smooth muscle myosin.(A and B) Tarantula thick filament (Protein Data Bank accession no. 3JBH). (C and D) 10S myosin (Protein Data Bank accession no. 6XE9). (A and C) Front views at same scale. (B and D) End views (same scale) obtained by rotating A and C 90° around the x axis so that pink IHM in A is closest to viewer (i.e., looking toward M-line). S2 in tarantula filament and segment 2 (Seg2) in 10S myosin both pass through a groove formed by the SH3 and converter (Cnv) domains of the BH motor domain (MD). The looser fit to the groove in tarantula may be due to the lower resolution of the reconstruction used to obtain the atomic model (20 Å resolution; cf. 4.3 Å for 10S myosin). Models in this figure were created with UCSF Chimera (Pettersen et al, 2004).

Comparison of tail interactions with the SH3 and converter domains in atomic models of tarantula thick filaments and 10S smooth muscle myosin. (A and B) Tarantula thick filament (Protein Data Bank accession no. 3JBH). (C and D) 10S myosin (Protein Data Bank accession no. 6XE9). (A and C) Front views at same scale. (B and D) End views (same scale) obtained by rotating A and C 90° around the x axis so that pink IHM in A is closest to viewer (i.e., looking toward M-line). S2 in tarantula filament and segment 2 (Seg2) in 10S myosin both pass through a groove formed by the SH3 and converter (Cnv) domains of the BH motor domain (MD). The looser fit to the groove in tarantula may be due to the lower resolution of the reconstruction used to obtain the atomic model (20 Å resolution; cf. 4.3 Å for 10S myosin). Models in this figure were created with UCSF Chimera (Pettersen et al, 2004).

This Feature Is Available To Subscribers Only

or Create an Account

Close Modal
Close Modal