Relationships between characteristics of CREs and determinants of CRSs. (A) The relationship between the average relative CRE amplitude Ārel and the corresponding value of CRS area per RYR (AC/R), number of RYRs per CRS (NRYR), iCa, and RYR group vicinity (ν). (B) The relationship between the characteristics of CREs and the corresponding RYR coupling strength φ values rectified with the optimized weight factor α = 0.67. The lines show the respective best-fit curves calculated by Eq. 9 for parameters given in Table 2. In A and B, yellow, blue, red, and green symbols denote data for iCa values of 0.04, 0.15, 0.25, and 0.40 pA, respectively. Squares and circles denote data for all wide and narrow CRSs (1,200 geometric models per CRS density type containing 10–80 RYRs). Diamonds and triangles denote data for the two types of compact CRSs (20 and 107 geometric models, respectively, containing 9–96 RYRs). Ārel, average Arel; Fb, the fraction of blips; Fq, the fraction of quarks; Fs, the fraction of sparks.
