Figure S4.
Competition EMSAs between truncated La proteins. (A) EMSA with 5′ fluorescently labeled miR-122, 2 nM La1–334, and increasing concentrations of La335–408. La335–408 was titrated from 448 pM to 2 µM. miR-122 migration was detected using in-gel fluorescence. (B) EMSA with 5′ fluorescently labeled miR-122, 2 nM La1–224, and increasing concentrations of La225–408. La225–408 was titrated from 448 pM to 2 µM. miR-122 migration was detected using in-gel fluorescence. Source data are available for this figure: SourceData FS4.

Competition EMSAs between truncated La proteins. (A) EMSA with 5′ fluorescently labeled miR-122, 2 nM La1–334, and increasing concentrations of La335–408. La335–408 was titrated from 448 pM to 2 µM. miR-122 migration was detected using in-gel fluorescence. (B) EMSA with 5′ fluorescently labeled miR-122, 2 nM La1–224, and increasing concentrations of La225–408. La225–408 was titrated from 448 pM to 2 µM. miR-122 migration was detected using in-gel fluorescence. Source data are available for this figure: SourceData FS4.

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