Figure 5.
La interacts with p62 in cells, in immunoisolated exosomes, and in vitro. (A) Immunoblot analysis of PNS inputs and IPs from lysed MDA-MB-231 cells. (B) Immunoblot analysis of exosome inputs and IPs from lysed exosomes isolated from the conditioned medium of MDA-MB-231 HA-CD63-mEGFPECL1 cells. (C) Immunoblot analysis of recombinant protein input and IPs from a La/p62 in vitro–binding assay. Source data are available for this figure: SourceData F5.