Figure 6.
![Figure 6. The β3 KKK motif participates in nAChR up-regulation. (A1, B1, C1, and D1) Representative TIRFM images of Neuro-2a cells transfected with α6-SEP and cotransfected with combinations of β2, β2β3, β3β2, β2β3[AAA], and β3AAA subunits. 50 nM nicotine was added 24 h after transfection. Bars, 10 µm. (A2, B2, C2, and D2) PMID for nAChRs (n = 11–27). ***, P < 0.0001 (ANOVA).](https://cdn.rupress.org/rup/content_public/journal/jgp/143/1/10.1085_jgp.201311102/5/jgp_201311102_fig6.jpeg?Expires=1773606083&Signature=1n9ml7AxcDxU19fNx8uO2d6UX9woXszIkzypNN2Oz2gdWHv7ZTrtPUuy6Jq77~sXjPL~s60~ho7CiHbznBoYNgTfwwk1F1-3oDSuSE9DPmnCeyYKl3PuIilLSUwU06XbcrftwghUyQc9dqGrUH2MZhBMLP1T~cgZjrlk2ndInr862JQvVeeVlPIjSeAZnlXfjNSEYaOSWOLslOqW4D2OJi-0d1lootr1tPzgP214qDUp-8wgIznJdHf8L91AatzJ3-PJrMA9~gRUS4Q32PSfF6A4ZDvKZMuaupwcWDcZKW4N7JmrECq9lPQOTTToiBfewx1PV9-5RUimtyP-jaQpDw__&Key-Pair-Id=APKAIE5G5CRDK6RD3PGA)
The β3 KKK motif participates in nAChR up-regulation. (A1, B1, C1, and D1) Representative TIRFM images of Neuro-2a cells transfected with α6-SEP and cotransfected with combinations of β2, β2β3, β3β2, β2β3[AAA], and β3AAA subunits. 50 nM nicotine was added 24 h after transfection. Bars, 10 µm. (A2, B2, C2, and D2) PMID for nAChRs (n = 11–27). ***, P < 0.0001 (ANOVA).
