Figure 3.
Expression of CD212 on activated T cells in healthy controls and patients by flow cytometry. (A) Gating of activated T cells using CD3 APC and CD69 FITC. (B–D) Patients with complete IL-12Rβ1 deficiency showing (B) absent, (C) reduced, and (D) normal expression of nonfunctional receptors on the surface of the cells in patients after stimulation with PHA and IL-2 compared with healthy controls. (E) Percent expression of CD212 in IL-12Rβ1 deficiency patients (Asterisks indicate statistical significance: ****P < 0.0001).

Expression of CD212 on activated T cells in healthy controls and patients by flow cytometry. (A) Gating of activated T cells using CD3 APC and CD69 FITC. (B–D) Patients with complete IL-12Rβ1 deficiency showing (B) absent, (C) reduced, and (D) normal expression of nonfunctional receptors on the surface of the cells in patients after stimulation with PHA and IL-2 compared with healthy controls. (E) Percent expression of CD212 in IL-12Rβ1 deficiency patients (Asterisks indicate statistical significance: ****P < 0.0001).

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