Transcriptional profile of heart cell populations after CXCR4 activation during AMI. (a) Experimental scheme. Indicated cell populations were sorted from control and infarcted hearts from ATI2341- and vehicle-treated mice. (b and c) UMAP visualization of the scRNAseq analysis of total cells colored by the group of origin (b) and treatment (c). (d) UMAP visualization of the scRNAseq analysis of total cells colored by type of cell (C0–C6) and top 8 genes expressed by each cluster. (e and f) Venn diagrams of detected genes in macrophages and neutrophils (e), and endothelial cells and fibroblasts (f) in control and AMI groups. (g and h) Volcano plot representing differentially expressed genes from detected genes in macrophages and neutrophils (g), and endothelial cells and fibroblasts (h) during AMI. Data in a–h are from a single experiment.