Figure 3.

Decay of intact proviruses in peripheral blood and LNs. (A–D) Results from peripheral blood. Individual best fits for each ΔGY-controller (A) and ΔGY-non-controller (B) and population best fits for ΔGY-controllers (C) and ΔGY-non-controllers (D). (E–H) Results from LNs. Individual best fits for each ΔGY-controller (E) and ΔGY-non-controller (F) and population best fits for ΔGY-controllers (G) and ΔGY-non-controllers (H). Each point is the geometric mean of ≥5 technical replicates, corrected for DNA shearing and env+ 2LTR circles and normalized per 106 CD4+ T cells. Bars are geometric standard deviation. Each decay phase is indicated by a color, with corresponding half-life indicated in respectively colored text. Gray shading represents 95% confidence bands. Vertical dotted lines represent ART initiation. Insert graphs in D and H are zoomed-in versions of the main graph.

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