Figure 1.
Study design and plasma SIV RNA levels. (A) Timeline of infection, ART initiation for ΔGY-non-controllers, and sampling of PBMCs (pink), peripheral LNs (blue), and plasma virus for sequencing (yellow). (B) Plasma SIV RNA levels through 66 wk after infection for controllers (blue) and non-controllers (orange). Each point is the mean of six technical replicates. The horizontal dotted line is the assay LOD (15 SIV RNA copies/ml). The vertical dotted line indicates ΔGY-non-controller ART initiation at 16 wk after infection. (C) Plasma SIV RNA measurements at peak viremia, day 21 after infection, and day 28 after infection. Shapes and colors are consistent with the key in B. Bars represent the geometric mean and geometric standard deviation. P values were determined using the Mann–Whitney nonparametric test.

Study design and plasma SIV RNA levels. (A) Timeline of infection, ART initiation for ΔGY-non-controllers, and sampling of PBMCs (pink), peripheral LNs (blue), and plasma virus for sequencing (yellow). (B) Plasma SIV RNA levels through 66 wk after infection for controllers (blue) and non-controllers (orange). Each point is the mean of six technical replicates. The horizontal dotted line is the assay LOD (15 SIV RNA copies/ml). The vertical dotted line indicates ΔGY-non-controller ART initiation at 16 wk after infection. (C) Plasma SIV RNA measurements at peak viremia, day 21 after infection, and day 28 after infection. Shapes and colors are consistent with the key in B. Bars represent the geometric mean and geometric standard deviation. P values were determined using the Mann–Whitney nonparametric test.

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