Figure S3.
Homozygosity of p120-catenin variants. (A–C)
Ctnnd1
Y112E/Y112E
embryos (A), Ctnnd1S288A/S288A embryos (B), and Ctnnd1K622A,K623A/K622A,K623A mutants (C) at E12.5 do not exhibit cleft lip. Arrows indicate exencephaly, which was observed in 1/6 embryos examined. Scale bar, 500 μm.