Frequency of additional noninfectious nonmalignant manifestations reported in literature. (A) Calculated median (range) percentage of patients and number of publications reported for each rheumatologic manifestation. (B) Calculated median (range) percentage of patients and number of publications reported for each allergy manifestation. (C) Calculated median (range) percentage of patients and number of publications reported for each skin manifestation. (D) Calculated median (range) percentage of patients and number of publications reported for each endocrine manifestation. AI, autoimmune.