Figure 6.

Dependence of AII AC oscillations on RBC-to-AII AC synaptic conductance and ON CBC membrane potential. (A) Representative simulation results under three different conditions (A1–A3). In each panel, the top trace shows the simulated AII AC membrane potential, and the bottom plot shows the corresponding PSD. The red square in PSD indicates the 5–15 Hz ROI used for analysis. (A1) Simulation with the membrane potential of −68 mV for RBC and −52 mV for ON CBC, and a gRBC to AII AC of 1.0 (comparable to WT). (A2) Simulation with the ON CBC membrane potential hyperpolarized to −58 mV. Other parameters are the same as in A1. (A3) Simulation with gRBC to AIIAC reduced to 0.1. Other parameters are the same as in A1. (B) Summary of the relationship between the strength of AII AC oscillations and the membrane potential of RBC and ON CBC. The synaptic conductance from RBC to AII AC was changed. The symbols indicate the simulated conditions shown in A1 (*), A2 (†), and A3 (‡). Color intensity represents the integrated value of the PSD calculated from the ROI.

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