Figure 2.
The predicted structure of human mitochondrial endoribonuclease complex, consisting of 11 protein subunits and one RNA subunit (RMRP, in violet). The position of the Finnish and Amish founder pathogenic variant n.71A>G is marked with light green borders, localizing in the very heart of the complex. The visualization was created using the AlphaFold Server (36) and is subject to AlphaFold Server Output Terms of Use (https://alphafoldserver.com/output-terms).