Figure 1.
![T cell counts in patients with HIGM-AT compared to patients without HIGM-AT (classic AT [C-AT]) and healthy controls. Counts are provided in cells/μl. The patient data are derived from multiple reports (6, 8, 12, 13, 16, 41, 42), with the counts provided in Table S1 (for HIGM-AT: N = 11 [CD3 counts], N = 17 [CD4/CD8 counts], N = 6 [naïve CD4/CD8 counts]; for C-AT: N = 12 [CD3 counts], N = 5 [naïve CD4/CD8 counts]). The healthy control (N = 5) counts are derived from Weitering et al. (2021) (12). Statistical testing was performed using GraphPad Prism, version 8.0.2. Kruskal–Wallis tests to compare all three groups and Mann–Whitney U tests to compare the HIGM-AT to the C-AT patients (*** = P-value <0.001).](https://cdn.rupress.org/rup/content_public/journal/jhi/1/4/10.70962_jhi.20250052/1/jhi_20250052_fig1.png?Expires=1768252462&Signature=4bazLy4Crx669WOcki4n5TtIRCPQE94tcp9C5M1GzxNQ-x0xe9kKq8Vbm-z5h9U-0VUo~y4AYh6BbEopvejBNN16EF9bat7nON21H6HxAXPKmGq45Cc3QIsbu9gKzbY4ES75g6gHpudp-brSOFnaxeRRLKJOE2atSMD5hlMXAK0~VBk0pV-ZO1bnfSaplePNI2mOTvnaF32YzHAqZkWS-Jr81y0Eh5JLz-yEATEpJxU7szNQG-Up-pdEQ7v8oec82gm3qxqEiSzjMnyyQuAiqqXipDDGW8l2yr~oah7WuMul6jSr~nxc1Y6G1lhqQXq5bWYBplLIiUg3VP6duDw-ZQ__&Key-Pair-Id=APKAIE5G5CRDK6RD3PGA)
T cell counts in patients with HIGM-AT compared to patients without HIGM-AT (classic AT [C-AT]) and healthy controls. Counts are provided in cells/μl. The patient data are derived from multiple reports (6, 8, 12, 13, 16, 41, 42), with the counts provided in Table S1 (for HIGM-AT: N = 11 [CD3 counts], N = 17 [CD4/CD8 counts], N = 6 [naïve CD4/CD8 counts]; for C-AT: N = 12 [CD3 counts], N = 5 [naïve CD4/CD8 counts]). The healthy control (N = 5) counts are derived from Weitering et al. (2021) (12). Statistical testing was performed using GraphPad Prism, version 8.0.2. Kruskal–Wallis tests to compare all three groups and Mann–Whitney U tests to compare the HIGM-AT to the C-AT patients (*** = P-value <0.001).