Figure 1.
Critical genes regulating the differentiation and functions of ILC. HSC, hematopoietic stem cell; GZNB, granzyme B; PRF1, perforin 1; NFIL3, nuclear factor, IL 3 regulated; TOX, thymocyte selection-associated high-mobility group box; TCF1, T cell factor 1; PLZF1, promyelocytic leukemia zinc finger; PD-1, programmed death; ICOS, inducible T cell co-stimulator; Rorα, RAR-related orphan receptor α; ICAM-1, intercellular adhesion molecule 1; RAG, recombination-activating genes; Rα, receptor α; Rβ, receptor β; Eomes, eomesodermin.