Figure 8.

Summary of identified NALCN/Cch1 channelosome subunits in eukaryotes. The presence of homologues identified in this study is indicated by green colored boxes, with taxonomic groupings according to recent phylogenomic studies (Li et al., 2021; Strassert et al., 2021; Al Jewari and Baldauf, 2023; Schultz et al., 2023). Boxes colored in gray indicate the presence of NALCN/Cch1-related channels within clade A of our phylogenetic analysis shown in Fig. 2 A. The box colored in orange represents a FAM155/Mid1 homologue previously identified for the apusomonad T. trahens (Ghezzi et al., 2014).

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