pheWAS of ADA2 pLOFs in the BioMe Biobank and the UK Biobank. (A) Gene-based pheWAS results in the BioMe Biobank (n = 27,742). (B) Gene-based pheWAS results in the UK Biobank (n = 189,440). The direction of the triangles indicates the direction of effect (up: increased risk, down: decreased risk). The red dashed line represents FDR-adjusted P value threshold, whereas the blue dashed line indicates the nominal significance level (P = 0.05). FDR, false discovery rate.
Figure S5.

pheWAS of ADA2 pLOFs in the BioMe Biobank and the UK Biobank. (A) Gene-based pheWAS results in the BioMe Biobank (n = 27,742). (B) Gene-based pheWAS results in the UK Biobank (n = 189,440). The direction of the triangles indicates the direction of effect (up: increased risk, down: decreased risk). The red dashed line represents FDR-adjusted P value threshold, whereas the blue dashed line indicates the nominal significance level (P = 0.05). FDR, false discovery rate.

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