Kaplan–Meier OS and EFS curves, stratified by baseline characteristics and treatment. (A and B) Kaplan–Meier OS and EFS curves, stratified by (A) donor group, indication for first HSCT, and domain of STAT1 mutation, and (B) HCT-CI score, conditioning regimen, and serotherapy, with log-rank P values. For OS, events are defined as death from any cause, and patients are censored at last date of follow-up. For EFS, events are defined as graft failure, re-transplant, acute GVHD grade III or IV, moderate to severe chronic GVHD, or death of any cause, whichever occurred first.