Figure 1.
The dual binding mode of NEDD1 to the γ-TuRC. (A) Model of the NEDD1 tetramer bound to MZT1 and to the N-terminal domain of GCP3. (B and C) Top and side views of the γ-TuRC (only γ-tubulin and the GCPs are shown) with bound NEDD1:MZT1:GCP3. The NEDD1 N-terminal WD40 domains are available to anchor the complex to microtubule-organizing centers.

The dual binding mode of NEDD1 to the γ-TuRC. (A) Model of the NEDD1 tetramer bound to MZT1 and to the N-terminal domain of GCP3. (B and C) Top and side views of the γ-TuRC (only γ-tubulin and the GCPs are shown) with bound NEDD1:MZT1:GCP3. The NEDD1 N-terminal WD40 domains are available to anchor the complex to microtubule-organizing centers.

This Feature Is Available To Subscribers Only

or Create an Account

Close Modal
Close Modal