Figure 1.
Neutralizing Auto-Abs against IFN-α2 and/or IFN-ω in critically ill patients with COVID-19. RLA is shown (ISRE dual luciferase activity, with normalization against Renilla luciferase activity) after stimulation with 10 ng/ml of IFN-α2 or IFN-ω in the presence of plasma samples (n = 209). RLA: relative luciferase activity. All samples were tested twice independently. Empty circles indicate patients who have died. The dotted line indicates the cutoff.

Neutralizing Auto-Abs against IFN-α2 and/or IFN-ω in critically ill patients with COVID-19. RLA is shown (ISRE dual luciferase activity, with normalization against Renilla luciferase activity) after stimulation with 10 ng/ml of IFN-α2 or IFN-ω in the presence of plasma samples (n = 209). RLA: relative luciferase activity. All samples were tested twice independently. Empty circles indicate patients who have died. The dotted line indicates the cutoff.

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