Reduced number of cDCs and moDCs but increased number of pDCs in IRF7-deficient mice. (A) The gating strategy of the flow cytometry data showing various myeloid cell populations such as conventional DCs (cDCs), pDCs, monocyte-derived DCs (moDCs), and iDCs. (B–F) Percentages and numbers of monocytes (B), iDCs, (C) cDCs, (D) moDCs (E), and pDCs (F) in 2- and 4-mo-old FcγRIIB^−/− and FcγRIIB^−/−IRF7^−/− mice (n = 8–9) are shown. (G) Gating strategy of B220⁺CD317⁺ (PDCA-1) pDCs are shown. Each symbol in B–F represents an individual mouse, and data are presented as means ± SEM. Data represent two to three experiments for each time point. P values were calculated via an unpaired Student’s t test or Mann–Whitney test (ns, not significant; *, P < 0.05; **, P < 0.01; ****, P < 0.0001).