Schematic of the proposed model. EcR signaling function in the AFCs modulates the clearance of underlying germline NCs in late oogenesis. EcR signaling function through Eip93F modulates the expression of phagocytic receptors (Drpr and Crq) in the AFC. This assists the invasion of AFCs between the germline NCs, which helps 4–5 AFCs to envelop a single NC. This stimulates the process of NC clearance with the initiation of extracellular acidification, NC nuclear membrane disassembly, and DNA fragmentation.