KEGG and GO analysis of downregulated genes in EcRB1 DN macrophages during larval and pupal stages. (A) KEGG analysis of downregulated genes upon expression of DN EcR in pupal macrophages. (B) STRING analysis of genes that are affected by EcRB1DN. Genes are directly related to cell death processes. (C) Fold changes of upregulated genes during larval and pupal transition in macrophages and downregulated genes in control and EcRB1DN pupal macrophage. Genes are related to cell death, JNK pathway, efferocytosis, and cytoskeleton rearrangement. Data are adapted from the Regan et. al. (2013) microarray data. (D) Venn diagram of three GO groups: apoptotic cell engulfment (GO:0043652), cell clearance (GO:0043277), and apoptotic processes (GO:0006915). (E) List of GO groups related to cell death and are affected by EcRB1DN