Chromatin accessibility. (A and B) Chromatin accessibility in Jurkat (A) and primary CD4⁺ T cell clones (B) as measured by ATAC-seq for the reporter construct at each integration site and control under resting conditions. (C) Graph shows ATAC-seq for ATP2B4 encompassing the reporter integration site in control and clones that carry the reporter in KDM2A, ATP2B4. Blue shading indicates the site of reporter integration. Graphs were generated by averaging the normalized reads from three technical replicates for each clone.