Figure S6.

[Ca 2+ ] time courses in various model compartments over a range of initial LSR [Ca 2+ ] as indicated in the legend. (A–E) Third dyad ring (i.e., the outer ring of a 25-member RyR2 cluster), (B) the TSR, (C) the cytoplasm, (D) the LSR, and (E) the Ca2+ flux through all RyR2s. (F) Total number of embers at z = 21 μm in the lead-up to the waves simulated in Fig. 6 A (red) and Fig. 6 B (blue).

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