Structural similarity between dEsyt C2A structure predicted by homology modeling and AlphaFold. (A) Structural superposition of the dEsyt C2A structure predicted by homology modeling and AlphaFold (RMSD = 0.62 Å). The structure derived from homology modeling is shown in magenta and that predicted by AlphaFold is shown in blue. Calcium ions are shown as dark blue spheres. The Ca²⁺ binding residues of the respective structures are shown in orange (homology model) and green (AlphaFold). (B) Structural superposition of the calcium-binding residues of the C2A domain from dEsyt. The Ca²⁺ binding residues of the respective structures are shown in orange (homology model) and green (AlphaFold). Calcium ions are shown as dark blue spheres.