T cell and NK cell infiltration in SARS-CoV-2–infected mice. (a) Representative flow cytometry plots for Fig. 3, g–i.(b) Relative percentage of different lymphoid cell populations in different knockout mice infected with SARS-CoV-2 2 DPI (WT [light gray] nontransduced, noninfected values from single experiment, n = 2; WT [dark gray] AAV-hACE2 and not infected values from two independent experiments, n = 4; WT [blue] AAV-hACE2 and infected values from two independent experiments, n = 4; IFNAR−/− values from three independent experiments, n = 6; and IRF3/7−/− values from two independent experiments, n = 5). (c) Relative percentage of lymphoid cell populations in WT mice transduced with AAV-hACE2 at 2, 4, and 7 d after SARS-CoV-2 infection (WT [light gray] nontransduced, noninfected values from single experiment,n = 2; WT [dark gray] AAV-hACE2 and not infected values from two independent experiments, n = 4; WT [blue] AAV-hACE2 and infected values from two independent experiments, n = 4, at each time point).