Figure 5.

Plots of the time course of changes in Vm, currents, and ion concentrations in simulations following removal of 3 mmol of K + from the extracellular compartment at time 0. The hyperKPP and WT lines are nearly identical on all the plots such that the black WT line cannot easily be seen. (A) Vm. (B) Net Na+ current. (C) Net K+ current. (D) Intracellular Na+ concentration. (E) Extracellular K+ concentration. (F) Na/K ATPase current.

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