Figure S3. Successful induction of liver... | Rockefeller University Press

Figure S3.

Successful induction of liver fibrosis and ICC. (A–C) Sirius red staining of paraffin liver sections from normal (A), CCl4-treated (B), and DDC-treated (C) Cd34creER;R26tdTomato mice. Scale bar = 200 µm (n = 5 mice from three independent experiments). (D) Photographs of normal and ICC-bearing livers (n = 5 mice from three independent experiments). (E and F) H&E staining of normal (E) and ICC-bearing (F) Cd34creER;R26tdTomato mice. Scale bar = 200 µm (n = 5 mice from three independent experiments). (G and H) Anti-Sox9 (G) and anti-Hnf4a (H) staining of paraffin sections of ICC-bearing livers. Scale bar = 100 µm (n = 5 mice from three independent experiments). Refer to the image caption for details.

Successful induction of liver fibrosis and ICC. (A–C) Sirius red staining of paraffin liver sections from normal (A), CCl₄-treated (B), and DDC-treated (C) Cd34^creER;R26^tdTomato mice. Scale bar = 200 µm (n = 5 mice from three independent experiments). (D) Photographs of normal and ICC-bearing livers (n = 5 mice from three independent experiments). (E and F) H&E staining of normal (E) and ICC-bearing (F) Cd34^creER;R26^tdTomato mice. Scale bar = 200 µm (n = 5 mice from three independent experiments). (G and H) Anti-Sox9 (G) and anti-Hnf4a (H) staining of paraffin sections of ICC-bearing livers. Scale bar = 100 µm (n = 5 mice from three independent experiments).