Mass-cytometry analysis of PBMC s from the patient and controls. (A) Uniform manifold approximation and projection (UMAP) of patient cells (P) and two representative controls (CTL1 and CTL2) with colors corresponding to the identified clusters (below the UMAPs). Arrows show clusters with obvious different proportions compared with controls on the patient UMAP. (B) Boxplot showing the relative abundance (proportion of all cells) of each identified cluster. The patient is in red, and controls are in black.