Figure 8.
Effects of ATG9A on the viability of mice and in a murine model of tuberculosis. (A) Survival curves of Atg9afl/fl LysM-Cre+ and Atg9afl/fl LysM-Cre− littermate mice uninfected or infected with M. tuberculosis Erdman aerosol (low dose/chronic infection; initial lung deposition, 225 CFU). (B) Survival curves of Atg9afl/fl LysM-Cre+ or Atg9afl/fl LysM-Cre− mice infected with M. tuberculosis Erdman aerosol (high dose/acute infection; initial lung deposition 2,491 CFU). CFU, colony forming units. Statistical test, Mantel–Cox. Source data are available for this figure: SourceData F8.