Additional types of profiles in electron micrographs from ultrastructural analyses. (A) HeLa^WT and HeLa^ATG9AKO cells. Note autophagosome and DGC in HeLa^WT cells and HDP and fewer DGC in HeLa^ATG9AKO. (B and C) HeLa cells knocked down for CHMP2A or IQGAP1. siRNA: siSCr control, CHPM2A or IQGAP1. A, autophagosome; DGC, degradative compartments; ER, endoplasmic reticulum; HDP, high density particle; M, mitochondria; N, nucleus; E, endosome; PM, plasma membrane. Scale bar, 500 nm. Source data are available for this figure: SourceData FS4.