Figure 9. SR Ca 2 release events at rest... | Rockefeller University Press

Figure 9.

SR Ca2+release events at rest in WT and DMDmdxmuscle fibers. (A) Green images show the spatial distribution of the SD of Fluo-4 fluorescence intensity throughout a sequence of 40 x,y consecutive confocal frames, in a WT and in a DMDmdx muscle fiber. Transmitted light images of the two fibers are shown on top. (B) Individual and corresponding mean (±SD) values for the relative fiber area exhibiting spontaneous Ca2+ release in the two groups (data are from 50 fibers from five animals in each group. P = 0.42, nested t test, 95% CI for the difference between mean values: −0.065 to 0.14). Each bar and superimposed data points correspond to data from a same animal. 95% CI, 95% confidence interval. Refer to the image caption for details.

SR Ca ²⁺ release events at rest in WT and DMD ^mdx muscle fibers. (A) Green images show the spatial distribution of the SD of Fluo-4 fluorescence intensity throughout a sequence of 40 x,y consecutive confocal frames, in a WT and in a DMD^mdx muscle fiber. Transmitted light images of the two fibers are shown on top. (B) Individual and corresponding mean (±SD) values for the relative fiber area exhibiting spontaneous Ca²⁺ release in the two groups (data are from 50 fibers from five animals in each group. P = 0.42, nested t test, 95% CI for the difference between mean values: −0.065 to 0.14). Each bar and superimposed data points correspond to data from a same animal. 95% CI, 95% confidence interval.