Mutations at N-linked glycan sites linked to clinical pathologies. (A) The N-linked glycan sites disrupted by mutations and their associated pathologies are listed. (B–D) The N-linked glycans affected by mutations (orange) in (B) NaV1.1; (C) NaV1.5 and (D) NaV1.6 are shown amongst the other N-linked glycans (grey) on the NaV channel surfaces.
Figure 7.

Mutations at N-linked glycan sites linked to clinical pathologies. (A) The N-linked glycan sites disrupted by mutations and their associated pathologies are listed. (B–D) The N-linked glycans affected by mutations (orange) in (B) NaV1.1; (C) NaV1.5 and (D) NaV1.6 are shown amongst the other N-linked glycans (grey) on the NaV channel surfaces.

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