Effects of FKBP12 deficiency on t-tubule structure. (A) FM-4-64-stained t-tubules in cardiomyocytes from hearts of FL, MCK-FKD, and MHC-FKD mice. (B–E) (B) Sarcomere spacing, (C) T-tubule regularity, (D) LE density, and (E) T-tubule integrity were analyzed using AutoTT (Guo and Song, 2014). Three male mice of each genotype were used for this study and a total of 23, 26, and 18 cardiomyocytes of the FL, MCK-FKD, and MHC-FKD mice. Data were analyzed with nested one-way ANOVAs with P values provided. Data are shown as mean ± SD.
Figure 4.

Effects of FKBP12 deficiency on t-tubule structure. (A) FM-4-64-stained t-tubules in cardiomyocytes from hearts of FL, MCK-FKD, and MHC-FKD mice. (B–E) (B) Sarcomere spacing, (C) T-tubule regularity, (D) LE density, and (E) T-tubule integrity were analyzed using AutoTT (Guo and Song, 2014). Three male mice of each genotype were used for this study and a total of 23, 26, and 18 cardiomyocytes of the FL, MCK-FKD, and MHC-FKD mice. Data were analyzed with nested one-way ANOVAs with P values provided. Data are shown as mean ± SD.

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