Figure 2.

Structure of the Nap1 2 •H2A-H2B•Kap114•Ran GTP complex. (A) The Nap12•H2A-H2B•Kap114•RanGTP structure, with the consensus/local refined maps (gray/cyan) overlayed and a cartoon schematic on the right. (B) The Nap12•H2A-H2B•Kap114 structure shown is as in A. (C) The RanGTP•Kap114•H2A-H2B structure (8F1E). (D) Kap114-Nap12 contacts (left) and H2A-H2B-Nap12 contacts (right) in the Nap12•H2A-H2B•Kap114 structure. Dashed lines show intermolecular contacts <4.0 Å (yellow) and <8.0 Å (light gray). See more in Figs. S2, S3, and S4.

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