Figure 4.
Simulations varying N, using v = 0 and κsys= 2 pN/nm. (A–H) Left panels are simulated time courses of force, F, and ergodicity, a (inset), and right panels are F and NMDP replotted and overlaid with Eqs. 1 (blue curve) and 2 (red curve) using N values of (A and B) 5, (C and D) 15, (E and F) 30, and (G and H) 100. In these simulations ∆Go = −5.7 RT and d = 8 nm which according to Eq. 2 gives Fo= −N∆Go/d = 3N pN when NAMD = NMDP. The simulated time courses of state occupancies are in Fig. S2.

Simulations varying N, using v = 0 and κ sys = 2 pN/nm. (A–H) Left panels are simulated time courses of force, F, and ergodicity, a (inset), and right panels are F and NMDP replotted and overlaid with Eqs. 1 (blue curve) and 2 (red curve) using N values of (A and B) 5, (C and D) 15, (E and F) 30, and (G and H) 100. In these simulations ∆Go = −5.7 RT and d = 8 nm which according to Eq. 2 gives Fo= −N∆Go/d = 3N pN when NAMD = NMDP. The simulated time courses of state occupancies are in Fig. S2.

This Feature Is Available To Subscribers Only

or Create an Account

Close Modal
Close Modal