Depletion of Rac2 inhibits tumor invasion. (A) Representative stills from time course imaging of ZMel1 cells after transplantation in rac2^+/+ or rac2^−/− larvae. (B) Quantification of number of invaded tumor cells in rac2^+/+ (n = 18 larvae), rac2^−/− (n = 23 larvae) and rac2+/− (n = 37 larvae) from three independent replicates. *P < 0.05, **P < 0.01. Scale bar = 20 µm.