Figure S3.
Effects of ML-SA5 treatment on PA-induced P-selectin expression, mitochondrial damage, and lysosomal acidification. (A) RT-qPCR analysis of P-selectin (SELP) expression level in HUVECs that were treated with PA (100 μM, 6 h) alone or with ML-SA5 (10 μM). (B) Effects of ML-SA5 treatment on PA-induced mitochondrial fragmentation. The effect of CCCP on mitochondrial fragmentation is shown for comparison. (C) Effects of ML-SA5 on LysoTracker labeling in HUVECs. Scale bar = 10 μm. Data are presented as means ± SEMs; ***P < 0.001.