No obvious visual impairments in mice after intracerebral injection of exogenous Aβ _1–42 during 3 days. (A–C) Actual photographs and quantitative analysis of optomotor responses at each grating density in mice 3 days after Aβ_1–42 injection (n = 8). (D–F) OCT images of mice’s retinas 3 days after Aβ_1–42 injection, with HE staining for retinal thickness measurement (n = 8). Data are representative of three independent experiments. All data are presented as mean ± SEM. Statistical significance was assessed using two-tailed unpaired t tests (E) or repeated measures ANOVA with Bonferroni post hoc tests (B, C, and F).