Novel genes regulate actin in the nucleus. (A) Images showing actin bars in the nucleus of S2R+ after gene depletion. Bar, 10 µm (B) Quantitation of bars of experiment represented in A. (C) Depletion of key genes induces actin accumulation in mammalian cells. Red is F-actin, blue is DNA, and green is GFP-actin. Bar, 20 µm.